Much has been learned about HIV/AIDS prevention since the epidemic began in the European Region more than two decades ago. Experience shows that the proper polices and strategies can prevent, slow and reverse HIV epidemics, and deliver high-quality treatment, care and support, even in resource-limited settings. Effective responses to HIV epidemics have been achieved through the implementation of proven, evidence-based interventions.

Effective HIV prevention interventions include condom use, provision of clean injecting equipment, opioid substitution therapy, treatment of sexually transmitted infections, and HIV testing and counselling. For more information, see also: Policy guidance for areas of intervention - Harm reduction.