Data and statistics
Rotavirus is a double-stranded RNA virus, spread via the faecal-oral route. Most human infections are caused by group A rotaviruses, which can be subdivided into strains based on two surface antigens (VP4 and VP7). This antigenic structure can change through mechanisms including antigenic shift and recombination with non-human strains, with implications for immunity.
Most reported rotavirus infections occur in young children under 5 years of age. Older children and adults are less likely to experience symptomatic infection, probably due to immunity gained through childhood infections.