The WHO Framework Convention on Tobacco Control and its guidelines provide the foundation for countries to implement and manage tobacco control. To help make this a reality, WHO introduced the MPOWER measures which correspond to one or more articles of the Framework Convention, to assist in reducing the demand for tobacco products at country-level. This updated brochure charts MPOWER’s journey to defeat the Global Tobacco Epidemic from 2007 to 2013. It sets out some examples of country successes and shows how, with the support of key partners and donors, MPOWER is having successes on the ground and showing impact.