EHEC outbreak: update 7

In Germany the outbreak of enterohaemorrhagic E. coli (EHEC) infection continues.

Haemolytic uraemic syndrome (HUS)

As of 03 June at 18:00 CET, Germany had reported 573 cases of HUS (including 12 fatalities):  53 more than the previous day. 70% of cases were in women and 89% in adults aged 20 years or older. The highest attack rates per 100 000 population were in the group aged 20–49 years.  Case onset dates ranged from 1 to 31 May.

Enterohaemorrhagic Escherichia coli (EHEC)

As of 03 June at 18:00 CET, 1428 cases of EHEC infection (without HUS) had been reported in Germany (with 6 fatalities): 215 more than the previous day. 61% of cases were in females and 88% in adults aged 20 years or older. Case onset dates ranged from 1 to 30 May. The Robert Koch Institute emphasized that it was still too early to judge whether the outbreak had peaked.

Other countries

As of 04 June at 18:00 CET, 11 other European countries had reported a total of  31 HUS (with 1 fatality) and 71 EHEC cases (with 0 fatalities):

 

Country
HUS
EHEC
Austria 0
2
Czech Republic 0
1
Denmark 7
11
France 0
10
Netherlands 4
4
Norway 0
1
Poland 1
0
Spain 1
0
Sweden 15
31
Switzerland 0
3
United Kingdom 3
8


In addition, the Centers for Disease Control and Prevention in Atlanta, United States of America, had earlier published information on 2 cases of HUS in the United States linked to this outbreak.

All except 1 of the above HUS and EHEC patients had travelled to or from Germany during the incubation period for infection, typically 3–4 days after exposure (range 2–10 days). An increasing number of cases is laboratory confirmed as EHEC serotype O104:H4 or, more precisely, a strain of enteroaggregative verocytotoxin-producing E. coli (EAggEC VTEC) O104:H4. All of the affected countries are reporting their cases to the German authorities and WHO. European Union countries are also sharing information through the secure Early Warning and Response System (EWRS).

Note

EHEC and HUS have exclusive notification categories, so case numbers should not overlap. the figures in any rapidly evolving outbreak, however, are provisional and subject to change for a variety of reasons.